Sec Form 4 Filing - Index Venture Associates III Ltd @ Minerva Neurosciences, Inc. - 2019-06-19

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person Index Venture Associates III Ltd 2. Issuer Name and Ticker or Trading Symbol Minerva Neurosciences, Inc. [ NERV] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director X __ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) C/O EFG WEALTH SOLUTIONS (JERSEY) LTD., 5TH FLOOR, 44 ESPLANADE 3. Date of Earliest Transaction (MM/DD/YY) 06/19/2019 (Street) ST. HELIER, Y9JE1 3FG 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) _____ Form filed by One Reporting Person __ X __ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 06/19/2019 S 77,243 ( 1 ) D $ 4.4425 ( 2 ) 4,129,764 ( 3 ) I See Footnote ( 4 ) Common Stock 06/20/2019 S 33,575 ( 5 ) D $ 4.3413 ( 6 ) 4,096,189 ( 7 ) I See Footnote ( 4 )

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other Index Venture Associates III Ltd C/O EFG WEALTH SOLUTIONS (JERSEY) LTD. 5TH FLOOR, 44 ESPLANADE ST. HELIER, Y9JE1 3FG X Index Venture Associates IV Ltd C/O INTERTRUST FUND SERVICES (JERSEY) LIMITED, 44 ESPLANADE ST. HELIER, Y9JE4 9WG X Index Venture Associates V Ltd C/O INTERTRUST FUND SERVICES (JERSEY) LIMITED, 44 ESPLANADE ST. HELIER, Y9JE4 9WG X Yucca (Jersey) SLP C/O INTERTRUST EMPLOYEE BENEFIT SERVICES LTD., 44 ESPLANADE ST. HELIER, Y9JE4 9WG X Signatures Index Venture Associates III Ltd., By: /s/ Nigel Greenwood, Director 06/21/2019 Signature of Reporting Person Date Index Venture Associates IV Ltd., By: /s/ Michael Johnson, Director 06/21/2019 Signature of Reporting Person Date Index Venture Associates V Ltd., By: /s/ Michael Johnson, Director 06/21/2019 Signature of Reporting Person Date YUCCA (JERSEY) SLP, By: Intertrust Employee Benefit Services Ltd., as authorized signatory of Yucca (Jersey) SLP in its capacity as Administrator of the Index Co-Investment Scheme, By: /s/ Sarah Earles, /s/ Michael Johnson, Its: Authorized Signatories 06/21/2019 Signature of Reporting Person Date

Explanation of Responses:

( 1 )Represents 13,389 shares sold by Index Ventures III (Jersey), L.P. ("Index III Jersey"), 27,198 shares sold by Index Ventures III (Delaware), L.P. ("Index III Delaware"), 484 shares sold by Index Ventures III Parallel Entrepreneur Fund (Jersey) L.P. ("Index III Parallel" and, together with Index III Jersey and Index III Delaware, the "Index III Funds"), 18,599 shares sold by Index Ventures IV (Jersey) L.P. ("Index IV Jersey"), 1,765 shares sold by Index Ventures IV Parallel Entrepreneur Fund (Jersey) L.P. ("Index IV Parallel" and, together with Index IV Jersey, the "Index IV Funds"), 14,708 shares sold by Index Ventures V (Jersey), L.P. ("Index V Jersey"), 119 shares sold by Index Ventures V Parallel Entrepreneur Fund (Jersey), L.P. ("Index V Parallel" and, together with Index V Jersey, the "Index V Funds") and 981 shares sold by Yucca (Jersey) SLP ("Yucca Jersey"). ( 2 )The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $4.31 to $4.555. The reporting persons undertake to provide to the issuer, any security holder of the issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. ( 3 )Represents 715,828 shares held directly by Index III Jersey, 1,454,132 shares held directly by Index III Delaware, 25,905 shares held directly by Index III Parallel, 994,363 shares held directly by Index IV Jersey, 94,385 shares held directly by Index IV Parallel, 786,353 shares held directly by Index V Jersey, 6,371 shares held directly by Index V Parallel and 52,427 shares held directly by Yucca Jersey. ( 4 )Index Venture Associates III Ltd. ("Index III GP") is the general partner of the Index III Funds, Index Venture Associates IV Ltd. ("Index IV GP") is the general partner of the Index IV Funds and Index Venture Associates V Ltd. ("Index V GP") is the general partner of the Index V Funds. Yucca (Jersey) SLP is the Administrator of the Index Co-Investment Scheme acting through Intertrust Employee Benefit Services Limited. Each of Index III GP, Index IV GP and Index V GP disclaims Section 16 beneficial ownership of the securities held by the Index III Funds, Index IV Funds and Index V Funds, respectively, and the shares held by Yucca Jersey, except to the extent of its respective pecuniary interest therein, if any, and this report shall not be deemed an admission that Index III GP, Index IV GP or Index V GP is the beneficial owner of such securities for Section 16 or any other purpose. ( 5 )Represents 5,818 shares sold by Index III Jersey, 11,823 shares sold by Index III Delaware, 211 shares sold by Index III Parallel, 8,084 shares sold by Index IV Jersey, 768 shares sold by Index IV Parallel, 6,395 shares sold by Index V Jersey, 51 shares sold by Index V Parallel and 425 shares sold by Yucca Jersey. ( 6 )The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $4.25 to $4.60. The reporting persons undertake to provide to the issuer, any security holder of the issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. ( 7 )Represents 710,010 shares held directly by Index III Jersey, 1,442,309 shares held directly by Index III Delaware, 25,694 shares held directly by Index III Parallel, 986,279 shares held directly by Index IV Jersey, 93,617 shares held directly by Index IV Parallel, 779,958 shares held directly by Index V Jersey, 6,320 shares held directly by Index V Parallel and 52,002 shares held directly by Yucca Jersey.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

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