Sec Form 4 Filing - Index Venture Associates III Ltd @ Minerva Neurosciences, Inc. - 2019-05-17

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL OMB Number: 3235-0287 Expires: November 30, 2011 Estimated average burden hours per response... 0.5

1. Name and Address of Reporting Person Index Venture Associates III Ltd 2. Issuer Name and Ticker or Trading Symbol Minerva Neurosciences, Inc. [ NERV] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director X __ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) C/O EFG WEALTH SOLUTIONS (JERSEY) LTD., 5TH FLOOR, 44 ESPLANADE 3. Date of Earliest Transaction (MM/DD/YY) 05/17/2019 (Street) ST. HELIER, Y9JE1 3FG 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) _____ Form filed by One Reporting Person __ X __ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 05/17/2019 S 22,718 ( 1 ) D $ 6.0164 ( 2 ) 4,451,643 ( 3 ) I See Footnote ( 4 ) Common Stock 05/20/2019 S 200 ( 5 ) D $ 6.075 4,451,443 ( 6 ) I See Footnote ( 4 )

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other Index Venture Associates III Ltd C/O EFG WEALTH SOLUTIONS (JERSEY) LTD. 5TH FLOOR, 44 ESPLANADE ST. HELIER, Y9JE1 3FG X Index Venture Associates IV Ltd C/O INTERTRUST FUND SERVICES (JERSEY) LIMITED, 44 ESPLANADE ST. HELIER, Y9JE4 9WG X Index Venture Associates V Ltd C/O INTERTRUST FUND SERVICES (JERSEY) LIMITED, 44 ESPLANADE ST. HELIER, Y9JE4 9WG X Yucca (Jersey) SLP C/O INTERTRUST EMPLOYEE BENEFIT SERVICES LTD., 44 ESPLANADE ST. HELIER, Y9JE4 9WG X Signatures Index Venture Associates III Ltd., By: /s/ Nigel Greenwood, Director 05/21/2019 Signature of Reporting Person Date Index Venture Associates IV Ltd., By: /s/ Michael Johnson, Director 05/21/2019 Signature of Reporting Person Date Index Venture Associates V Ltd., By: /s/ Michael Johnson, Director 05/21/2019 Signature of Reporting Person Date YUCCA (JERSEY) SLP, By Intertrust Employee Benefit Services Limited, as authorized signatory of Yucca (Jersey) SLP in its capacity as Administrator of the Index Co-Investment Scheme, By: /s/ Sarah Earles, /s/ Michael Johnson, Its: Authorized Signatories 05/21/2019 Signature of Reporting Person Date

Explanation of Responses:

( 1 )Represents 3,938 shares sold by Index Ventures III (Jersey), L.P. ("Index III Jersey"), 7,999 shares sold by Index Ventures III (Delaware), L.P. ("Index III Delaware"), 143 shares sold by Index Ventures III Parallel Entrepreneur Fund (Jersey) L.P. ("Index III Parallel" and, together with Index III Jersey and Index III Delaware, the "Index III Funds"), 5,470 shares sold by Index Ventures IV (Jersey) L.P. ("Index IV Jersey"), 519 shares sold by Index Ventures IV Parallel Entrepreneur Fund (Jersey) L.P. ("Index IV Parallel" and, together with Index IV Jersey, the "Index IV Funds"), 4,326 shares sold by Index Ventures V (Jersey), L.P. ("Index V Jersey"), 35 shares sold by Index Ventures V Parallel Entrepreneur Fund (Jersey), L.P. ("Index V Parallel" and, together with Index V Jersey, the "Index V Funds") and 288 shares sold by Yucca (Jersey) SLP ("Yucca Jersey"). ( 2 )The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $6.00 to $6.25. The reporting persons undertake to provide to the issuer, any security holder of the issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. ( 3 )Represents 771,621 shares held directly by Index III Jersey, 1,567,468 shares held directly by Index III Delaware, 27,923 shares held directly by Index III Parallel, 1,071,865 shares held directly by Index IV Jersey, 101,741 shares held directly by Index IV Parallel, 847,641 shares held directly by Index V Jersey, 6,868 shares held directly by Index V Parallel and 56,516 shares held directly by Yucca Jersey. ( 4 )Index Venture Associates III Ltd. ("Index III GP") is the general partner of the Index III Funds, Index Venture Associates IV Ltd. ("Index IV GP") is the general partner of the Index IV Funds and Index Venture Associates V Ltd. ("Index V GP") is the general partner of the Index V Funds. Yucca (Jersey) SLP is the Administrator of the Index Co-Investment Scheme acting through Intertrust Employee Benefit Services Limited. Each of Index III GP, Index IV GP and Index V GP disclaims Section 16 beneficial ownership of the securities held by the Index III Funds, Index IV Funds and Index V Funds, respectively, and the shares held by Yucca Jersey, except to the extent of its respective pecuniary interest therein, if any, and this report shall not be deemed an admission that Index III GP, Index IV GP or Index V GP is the beneficial owner of such securities for Section 16 or any other purpose. ( 5 )Represents 35 shares sold by Index III Jersey, 70 shares sold by Index III Delaware, 1 share sold by Index III Parallel, 48 shares sold by Index IV Jersey, 5 shares sold by Index IV Parallel, 38 shares sold by Index V Jersey, 0 shares sold by Index V Parallel and 3 shares sold by Yucca Jersey. ( 6 )Represents 771,586 shares held directly by Index III Jersey, 1,567,398 shares held directly by Index III Delaware, 27,922 shares held directly by Index III Parallel, 1,071,817 shares held directly by Index IV Jersey, 101,736 shares held directly by Index IV Parallel, 847,603 shares held directly by Index V Jersey, 6,868 shares held directly by Index V Parallel and 56,513 shares held directly by Yucca Jersey.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.