Sec Form 4 Filing - Petry Harald @ uniQure N.V. - 2017-03-21

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person Petry Harald 2. Issuer Name and Ticker or Trading Symbol uniQure N.V. [ QURE] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner X __ Officer (give title below) _____ Other (specify below) Chief Scientific Officer (Last) (First) (Middle) C/O UNIQURE N.V., MEIBERGDREFF 61 3. Date of Earliest Transaction (MM/DD/YY) 03/21/2017 (Street) AMSTERDAM, P7P7 1005 BA 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Ordinary Shares 03/21/2017 M 25,422 A $ 3.2963 ( 1 ) 25,422 D Ordinary Shares 03/21/2017 S( 2 ) 25,422 D $ 6.0298 ( 3 ) 0 D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Stock Option (right to buy) $ 3.2963 ( 1 ) 03/21/2017 M 25,422 ( 4 ) 05/04/2022 Ordinary Shares 25,422 $ 0 115,230 D

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other Petry Harald C/O UNIQURE N.V. MEIBERGDREFF 61 AMSTERDAM, P7P7 1005 BA Chief Scientific Officer Signatures /s/ Maiken Keson-Brookes, attorney-in-fact 06/08/2017 Signature of Reporting Person Date

Explanation of Responses:

( 1 )The Stock Option was exercised at a price of 3.07 Euros per share. The conversion from Euro to U.S. dollars ($) applied the exchange rate of 1.0737 Euros to U.S. dollars as of the exercise date (the "Exchange Rate"). ( 2 )The sales reported in this Form 4 were pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 3, 2017. ( 3 )The shares were sold at a price of 5.6159 Euros per share. The conversion from Euro to U.S. dollars applied the Exchange Rate. ( 4 )The Stock Option vested in full on February 6, 2014.

Remarks: Exhibit List:Exhibit 24 - Power of Attorney

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

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