Sec Form 4 Filing - MIDDLETON FRED A @ CalciMedica, Inc. /DE/ - 2023-03-20

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person MIDDLETON FRED A 2. Issuer Name and Ticker or Trading Symbol CalciMedica, Inc. /DE/ [ CALC] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) X __ Director X __ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) C/O CALCIMEDICA, INC., 505 COAST S. BLVD. #202 3. Date of Earliest Transaction (MM/DD/YY) 03/20/2023 (Street) LA JOLLA, CA92037 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 03/20/2023 A 703,388 A 703,388 I By Sanderling Venture Partners VI, L.P. ( 2 ) Common Stock 03/20/2023 A 582,757 A 582,757 I By Sanderling Venture Partners VI Co-Investment Fund, L.P. ( 4 ) Common Stock 03/20/2023 A 17,682 A 17,682 I By Sanderling Ventures Management VI ( 4 ) Common Stock 03/20/2023 A 7,456 A 7,456 I By Sanderling VI Beteligungs GmbH & Co KG ( 4 ) Common Stock 03/20/2023 A 8,884 A 8,884 I By Sanderling VI Limited Partnership ( 4 ) Common Stock 03/20/2023 A 256,852 A 256,852 I By Sanderling Ventures VII, L.P. ( 9 ) Common Stock 03/20/2023 A 14,425 A 14,425 I By Sanderling Ventures VII Annex Fund, L.P. ( 11 ) Common Stock 03/20/2023 A 47,052 A 47,052 I By Sanderling Ventures VII (Canada), L.P. ( 11 ) Common Stock 03/20/2023 A 1,548 A 1,548 I By Sanderling Ventures Management VII ( 11 ) Common Stock 03/20/2023 A 8,176 A 8,176 I By Golden Triangle Ventures, LLC ( 15 )

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Warrant $ 10.42 03/20/2023 A 5,760 ( 16 ) 10/24/2032 Common Stock 5,760 ( 17 ) 5,760 D Warrant $ 26.74 03/20/2023 A 2,672 ( 16 ) 02/28/2027 Common Stock 2,672 ( 18 ) 2,672 I By Sanderling Venture Partners VI, LP ( 4 ) Warrant $ 27.94 03/20/2023 A 16,539 ( 16 ) 02/22/2026 Common Stock 16,539 ( 19 ) 16,539 I By Sanderling Venture Partners VI, LP ( 4 ) Warrant $ 27.94 03/20/2023 A 2,685 ( 16 ) 06/25/2026 Common Stock 2,685 ( 20 ) 2,685 I By Sanderling Venture Partners VI, LP ( 4 ) Warrant $ 26.74 03/20/2023 A 1,910 ( 16 ) 02/28/2027 Common Stock 1,910 ( 21 ) 1,910 I By Sanderling Venture Partners VI Co-Investment Fund, L.P. ( 4 ) Warrant $ 27.94 03/20/2023 A 6,852 ( 16 ) 02/22/2026 Common Stock 6,852 ( 22 ) 6,852 I By Sanderling Venture Partners VI Co-Investment Fund, L.P. ( 4 ) Warrant $ 27.94 03/20/2023 A 15,403 ( 16 ) 06/25/2026 Common Stock 15,403 ( 23 ) 15,403 I By Sanderling Venture Partners VI Co-Investment Fund, L.P. ( 4 ) Warrant $ 27.94 03/20/2023 A 237 ( 16 ) 03/04/2026 Common Stock 237 ( 24 ) 237 I By Sanderling Ventures Management VI ( 4 ) Warrant $ 27.94 03/20/2023 A 183 ( 16 ) 06/25/2026 Common Stock 183 ( 25 ) 183 I By Sanderling Ventures Management VI ( 4 ) Warrant $ 27.94 03/20/2023 A 8,393 ( 16 ) 02/22/2026 Common Stock 8,393 ( 26 ) 8,393 I By Sanderling Ventures VII, LP ( 11 ) Warrant $ 27.94 03/20/2023 A 12,380 ( 16 ) 06/25/2026 Common Stock 12,380 ( 27 ) 12,380 I By Sanderling Ventures VII, LP ( 11 ) Warrant $ 27.94 03/20/2023 A 2,203 ( 16 ) 03/04/2026 Common Stock 2,203 ( 28 ) 2,203 I By Sanderling Ventures VII (Canada), LP ( 11 ) Warrant $ 27.94 03/20/2023 A 3,249 ( 16 ) 06/25/2026 Common Stock 3,249 ( 29 ) 3,249 I By Sanderling Ventures VII (Canada), LP ( 11 ) Warrant $ 27.94 03/20/2023 A 569 ( 16 ) 03/04/2026 Common Stock 569 ( 30 ) 569 I By Sanderling Ventures VII Annex Fund, L.P. ( 11 ) Warrant $ 27.94 03/20/2023 A 840 ( 16 ) 06/25/2026 Common Stock 840 ( 31 ) 840 I By Sanderling Ventures VII Annex Fund, L.P. ( 11 ) Warrant $ 27.94 03/20/2023 A 113 ( 16 ) 03/04/2026 Common Stock 113 ( 32 ) 113 I By Sanderling Ventures Management VII ( 11 ) Warrant $ 27.94 03/20/2023 A 167 ( 16 ) 06/25/2026 Common Stock 167 ( 33 ) 167 I By Sanderling Ventu res Management VII ( 11 )

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other MIDDLETON FRED A C/O CALCIMEDICA, INC. 505 COAST S. BLVD. #202 LA JOLLA, CA92037 X X Signatures By John Dunn, Attorney-in-Fact 03/22/2023 Signature of Reporting Person Date

Explanation of Responses:

( 1 )Received in exchange for 24,423,158 shares of common stock of CalciMedica, Inc. ("CalciMedica") pursuant to an Agreement and Plan of Merger and Reorganization (the "Merger Agreement") by and among CalciMedica, the Issuer and Camaro Merger Sub, Inc., a wholly-owned subsidiary of the Issuer ("Merger Sub"). Under the terms of the Merger Agreement, on March 20, 2023, Merger Sub merged with and into CalciMedica (the "Merger"), with CalciMedica surviving the Merger as a wholly-owned subsidiary of the Issuer. Upon the closing of the Merger, each share of CalciMedica common stock was converted into the right to receive 0.0288 of a share of the Issuer's common stock. Subsequent to the Merger, the name of the Issuer was changed from Graybug Vision, Inc. to CalciMedica, Inc. ( 2 )The Reporting Person, a director of Sanderling Ventures, may be deemed to beneficially own the securities of the Issuer held by Sanderling Venture Partners VI, LP ("SVP VI, LP", together with Sanderling Venture Partners VI Co-Investment Fund, L.P., Sanderling VI Beteiligungs GmbH & Co. KG, Sanderling Ventures Management VI and Sanderling VI Limited Partnership (the "Sanderling VI Shares"). The Reporting Person disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein. ( 3 )Received in exchange for 20,234,606 shares of the common stock of CalciMedica pursuant to the Merger Agreement. ( 4 )The Reporting Person, a director of Sanderling Ventures, may be deemed to beneficially own the Sanderling VI Securities. The Reporting Person disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein. ( 5 )Received in exchange for 613,943 shares of the common stock of CalciMedica pursuant to the Merger Agreement. ( 6 )Received in exchange for 258,883 shares of the common stock of CalciMedica pursuant to the Merger Agreement. ( 7 )Received in exchange for 308,455 shares of the common stock of CalciMedica pursuant to the Merger Agreement. ( 8 )Received in exchange for 8,918,437 shares of the common stock of CalciMedica pursuant to the Merger Agreement. ( 9 )The Reporting Person, a director of Sanderling Ventures, may be deemed to beneficially own the securities of the Issuer held by Sanderling Ventures VII, LP ("SVP VII, LP", together with Sanderling Ventures Management VII, Sanderling Ventures VII (Canada), L.P. and Sanderling Ventures VII Annex Fund, L.P., the "Sanderling VII Shares"). The Reporting Person disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein. ( 10 )Received in exchange for 500,854 shares of the common stock of CalciMedica pursuant to the Merger Agreement. ( 11 )The Reporting Person, a director of Sanderling Ventures, may be deemed to beneficially own the Sanderling VII Securities. The Reporting Person disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein. ( 12 )Received in exchange for 1,633,699 shares of the common stock of CalciMedica pursuant to the Merger Agreement. ( 13 )Received in exchange for 53,733 shares of the common stock of CalciMedica pursuant to the Merger Agreement. ( 14 )Received in exchange for 283,866 shares of the common stock of CalciMedica pursuant to the Merger Agreement. ( 15 )The Reporting Person is a managing member of Golden Triangle Ventures LLC and may be deemed to beneficially own the securities of the Issuer held by Golden Triangle Ventures LLC. The Reporting Person disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein. ( 16 )Immediately exercisable. ( 17 )Received in exchange for a warrant to purchase 200,000 shares of common stock of CalciMedica pursuant to the Merger Agreement. ( 18 )Received in exchange for a warrant to purchase 92,748 shares of common stock of CalciMedica pursuant to the Merger Agreement. ( 19 )Received in exchange for a warrant to purchase 574,296 shares of common stock of CalciMedica pursuant to the Merger Agreement. ( 20 )Received in exchange for a warrant to purchase 93,225 shares of common stock of CalciMedica pursuant to the Merger Agreement. ( 21 )Received in exchange for a warrant to purchase 66,305 shares of common stock of CalciMedica pursuant to the Merger Agreement. ( 22 )Received in exchange for a warrant to purchase 237,911 shares of common stock of CalciMedica pursuant to the Merger Agreement. ( 23 )Received in exchange for a warrant to purchase 534,815 shares of common stock of CalciMedica pursuant to the Merger Agreement. ( 24 )Received in exchange for a warrant to purchase 8,203 shares of common stock of CalciMedica pursuant to the Merger Agreement. ( 25 )Received in exchange for a warrant to purchase 6,343 shares of common stock of CalciMedica pursuant to the Merger Agreement. ( 26 )Received in exchange for a warrant to purchase 291,407 shares of common stock of CalciMedica pursuant to the Merger Agreement. ( 27 )Received in exchange for a warrant to purchase 429,837 shares of common stock of CalciMedica pursuant to the Merger Agreement. ( 28 )Received in exchange for a warrant to purchase 76,470 shares of common stock of CalciMedica pursuant to the Merger Agreement. ( 29 )Received in exchange for a warrant to purchase 112,796 shares of common stock of CalciMedica pursuant to the Merger Agreement. ( 30 )Received in exchange for a warrant to purchase 19,754 shares of common stock of CalciMedica pursuant to the Merger Agreement. ( 31 )Received in exchange for a warrant to purchase 29,139 shares of common stock of CalciMedica pursuant to the Merger Agreement. ( 32 )Received in exchange for a warrant to purchase 3,915 shares of common stock of CalciMedica pursuant to the Merger Agreement. ( 33 )Received in exchange for a warrant to purchase 5,775 shares of common stock of CalciMedica pursuant to the Merger Agreement.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

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