Reporting Owners Reporting Owner Name / Address | Relationships | Director | 10% Owner | Officer | Other | HealthCor Management, L.P. 152 W. 57TH STREET, 43RD FLOOR NEW YORK, NY10019 | | X | | | HealthCor Associates, LLC 152 W. 57TH STREET, 43RD FLOOR NEW YORK, NY10019 | | X | | | HealthCor Hybrid Offshore Master Fund, L.P. 152 W. 57TH STREET, 43RD FLOOR NEW YORK, NY10019 | | X | | | HealthCor Hybrid Offshore GP, LLC 152 W. 57TH STREET, 43RD FLOOR NEW YORK, NY10019 | | X | | | HealthCor Group, LLC 152 W. 57TH STREET, 43RD FLOOR NEW YORK, NY10019 | | X | | | HealthCor Partners Management LP 152 W. 57TH STREET, 43RD FLOOR NEW YORK, NY10019 | | X | | | HealthCor Partners Management GP, LLC 152 W. 57TH STREET, 43RD FLOOR NEW YORK, NY10019 | | X | | | HealthCor Partners Fund LP 152 W. 57TH STREET, 43RD FLOOR NEW YORK, NY10019 | | X | | | HealthCor Partners LP 152 W. 57TH STREET, 43RD FLOOR NEW YORK, NY10019 | | X | | | | Signatures HealthCor Management, L.P., By: HealthCor Associates, LLC, its general partner, By: /s/ Anabelle P. Gray, General Counsel | | 03/02/2017 | ** Signature of Reporting Person | Date | HealthCor Associates, LLC, By: /s/ Anabelle P. Gray, General Counsel | | 03/02/2017 | ** Signature of Reporting Person | Date | HealthCor Hybrid Offshore GP, LLC, for itself and as general partner on behalf of HealthCor Hybrid Offshore Master Fund, L.P., By: HealthCor Group, LLC, its general partner, By: /s/ Anabelle P. Gray, General Counsel | | 03/02/2017 | ** Signature of Reporting Person | Date | HealthCor Group, LLC, By: /s/ Anabelle P. Gray, General Counsel | | 03/02/2017 | ** Signature of Reporting Person | Date | HealthCor Partners Management LP, By: HealthCor Partners Management GP, LLC, its general partner, By: /s/ Anabelle P. Gray, General Counsel | | 03/02/2017 | ** Signature of Reporting Person | Date | HealthCor Partners Management GP, LLC, By: /s/ Anabelle P. Gray, General Counsel | | 03/02/2017 | ** Signature of Reporting Person | Date | HealthCor Partners L.P., for itself, and as general partner on behalf of Healthcor Partners Fund, L.P., By: HealthCor Partners GP, LLC, its general partner, By: /s/ Anabelle P. Gray, General Counsel | | 03/02/2017 | ** Signature of Reporting Person | Date | |