Sec Form 4 Filing - Smith Edward B III @ HEAT BIOLOGICS, INC. - 2017-04-28

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person Smith Edward B III 2. Issuer Name and Ticker or Trading Symbol HEAT BIOLOGICS, INC. [ HTBX] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) X __ Director _____ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) C/O HEAT BIOLOGICS, INC., 801 CAPITOLA DRIVE 3. Date of Earliest Transaction (MM/DD/YY) 04/28/2017 (Street) DURHAM, NC27713 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 04/28/2017 A 10,010 ( 1 ) ( 2 ) A 10,010 ( 1 ) ( 2 ) D Common Stock 04/28/2017 A 335,743 ( 1 ) ( 2 ) A 1,033,046 ( 1 ) ( 2 ) ( 3 ) I See footnotes ( 3 ) ( 4 )

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other Smith Edward B III C/O HEAT BIOLOGICS, INC. 801 CAPITOLA DRIVE DURHAM, NC27713 X Signatures /s/ Edward B. Smith III 05/02/2017 Signature of Reporting Person Date

Explanation of Responses:

( 1 )On March 7, 2017, Heat Biologics, Inc. (the "Company") entered into a Stock Purchase Agreement, as amended, with Pelican Therapeutics, Inc. ("Pelican"), and certain holders of the outstanding capital stock of Pelican, including Mr. Smith and Aristar (as defined below), who agreed to sell their shares in Pelican to the Company (the "Acquisition"). Edward B. Smith, a member of the Company's board of directors, individually and through his affiliated entity, Aristar Ventures III, LLC ("Aristar"), is a holder of Pelican outstanding capital stock. ( 2 )(Continued from footnote (1)) In connection with the closing of the Acquisition, which occurred on April 28, 2017, Mr. Smith and Aristar sold approximately 85% of their shares of capital stock in Pelican (which they held directly and through a limited liability company) in exchange for cash consideration and 10,010 shares and 335,743 shares, respectively, of the Company's common stock, $0.0002 par value per share (the "Common Stock"). All of the shares of Common Stock issued in the Acquisition are currently held in escrow and are subject to forfeiture during the six month period following the Acquisition to satisfy certain indemnification obligations. ( 3 )Held by Aristar. Mr. Smith serves as the managing member of Aristar. ( 4 )Mr. Smith is deemed to beneficially own the shares held by Aristar in his role as the managing member since he has the control over the voting and disposition of any shares of Common Stock held by Aristar. Mr. Smith disclaims beneficial ownership of the shares of Common Stock held by Aristar except to the extent of any pecuniary interest (as defined in Rule 16a-1(a)(2) promulgated under the Securities Exchange Act of 1934, as amended) that he may have in such entity.

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