Sec Form 4 Filing - EVNIN LUKE @ Pacira Pharmaceuticals, Inc. - 2013-04-12

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person EVNIN LUKE 2. Issuer Name and Ticker or Trading Symbol Pacira Pharmaceuticals, Inc. [ PCRX] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) X __ Director _____ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) C/O MPM ASSET MANAGEMENT, 200 CLARENDON STREET, 54TH FLOOR 3. Date of Earliest Transaction (MM/DD/YY) 04/12/2013 (Street) BOSTON, MA02116 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 04/12/2013 X 37,192 ( 1 ) A $ 2.69 1,317,671 I See Footnote ( 2 ) ( 3 ) Common Stock 04/12/2013 S( 4 ) 3,416 ( 4 ) D $ 29.3 1,314,255 I See Footnote ( 3 ) ( 5 ) Common Stock 22,746 D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Common Stock Warrants (Right to Buy) $ 2.69 04/12/2013 X 37,192 ( 1 ) 01/22/2009 01/21/2014 Common Stock 37,192 $ 0 0 I See Footnote ( 1 )

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other EVNIN LUKE C/O MPM ASSET MANAGEMENT 200 CLARENDON STREET, 54TH FLOOR BOSTON, MA02116 X Signatures /s/ Luke Evnin 05/08/2013 Signature of Reporting Person Date

Explanation of Responses:

( 1 )The warrants were held and exercised as follows: 34,858 by MPM BioVentures IV-QP, L.P. ("BV IV QP"), 1,343 by MPM BioVentures IV GmbH & Co. Beteiligungs KG ("BV IV KG") and 991 by MPM Asset Management Investors BV4 LLC ("AM BV4"). MPM BioVentures IV GP LLC and MPM BioVentures IV LLC ("BV LLC") are the direct and indirect general partners of BV IV QP and BV IV KG and BV LLC is the manager of AM BV4. The Reporting Person is a member of BV LLC. ( 2 )The shares are held as follows: 1,234,997 by BV IV QP, 47,582 by BV IV KG and 35,092 by AM BV4. The Reporting Person disclaims beneficial ownership of the securities except to the extent of his pecuniary interest therein. ( 3 )Does not reflect previously reported transactions that occurred after April 12, 2013 and the Form 4s filed by the Reporting Person reporting such transactions failed to take into account the transactions reported hereby. Accordingly, the Form 4s filed by the Reporting Person on April 18, 2013 and April 29, 2013 understated the number of shares beneficially owned following the transactions reported therein by an aggregate of 33,776 shares. ( 4 )On April 12, 2013, the following warrants to purchase shares of PCRX common stock were exercised for $2.69 per share: 34,858 by BV IV QP, 1,343 by BV IV KG and 991 by AM BV4. The exercise price was paid on a cashless basis, resulting in PCRX's withholding of the following warrant shares to pay the exercise price: 3,201 for BV IV QP, 124 for BV IV KG and 91 for AM BV4. ( 5 )The shares are held as follows: 1,231,796 by BV IV QP, 47,458 by BV IV KG and 35,001 by AM BV4. The Reporting Person disclaims beneficial ownership of the securities except to the extent of his pecuniary interest therein.

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