Sec Form 4 Filing - Palmetto Partners, Ltd. @ XERIS PHARMACEUTICALS INC - 2018-06-25

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person Palmetto Partners, Ltd. 2. Issuer Name and Ticker or Trading Symbol XERIS PHARMACEUTICALS INC [ XERS] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director X __ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) 109 N. POST OAK LANE, SUITE 600 3. Date of Earliest Transaction (MM/DD/YY) 06/25/2018 (Street) HOUSTON, TX77024 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) _____ Form filed by One Reporting Person __ X __ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock ( 1 ) 06/25/2018 C 930,383 A 930,383 ( 1 ) D Common Stock ( 3 ) 06/25/2018 C 581,992 A 1,512,375 ( 3 ) D Common Stock ( 4 ) 06/25/2018 C 447,686 A 1,960,061 ( 4 ) D Common Stock ( 4 ) 06/25/2018 P 150,000 A $ 15 2,110,061 ( 4 ) D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Series A Preferred Stock ( 1 ) ( 2 ) 06/25/2018 C 1,657,125 ( 2 ) ( 2 ) Common Stock 930,383 ( 2 ) 0 D Series B Preferred Stock ( 3 ) ( 2 ) 06/25/2018 C 1,036,599 ( 2 ) ( 2 ) Common Stock 581,992 ( 2 ) 0 D Series B Preferred Stock ( 4 ) ( 2 ) 06/25/2018 C 797,384 ( 2 ) ( 2 ) Common Stock 447,686 ( 2 ) 0 D

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other Palmetto Partners, Ltd. 109 N. POST OAK LANE, SUITE 600 HOUSTON, TX77024 X Palmetto Partners 2014, LP 109 N. POST OAK LANE, SUITE 600 HOUSTON, TX77024 X Palmetto Partners 2015, LP 109 N. POST OAK LANE, SUITE 600 HOUSTON, TX77024 X Signatures Palmetto Partners, Ltd., by /s/ Ben D. Smolij, attorney in fact 06/25/2018 Signature of Reporting Person Date Palmetto Partners 2014, LP, by /s/ Ben D. Smolij, attorney in fact 06/25/2018 Signature of Reporting Person Date Palmetto Partners 2015, LP, by /s/ Ben D. Smolij, attorney in fact 06/25/2018 Signature of Reporting Person Date

Explanation of Responses:

( 1 )The securities are owned by Palmetto Partners, 2014, LP, who is a member of a group with Palmetto Partners, Ltd. and Palmetto Partners 2015, LP. ( 2 )Each share of Preferred Stock automatically converted into Common Stock, for no additional payment or consideration, on a 1.78112-for-1 basis, at the closing of the Issuer's initial public offering on June 25, 2018 and had no expiration date. ( 3 )The securities are owned by Palmetto Partners 2015, LP, who is a member of a group with Palmetto Partners, Ltd. and Palmetto Partners 2014, LP. ( 4 )The securities are owned by Palmetto Partners, Ltd., who is a member of a group with Palmetto Partners 2014, LP and Palmetto Partners 2015, LP.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

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