Sec Form 3 Filing - PRUDENTIAL FINANCIAL INC @ Kayne Anderson MLP/Midstream Investment Co - 2020-02-11

FORM 3 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person PRUDENTIAL FINANCIAL INC 2. Issuer Name and Ticker or Trading Symbol Kayne Anderson MLP/Midstream Investment Co [ KYN] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director X __ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) 751 BROAD ST, 3. Date of Earliest Transaction (MM/DD/YY) 02/11/2020 (Street) NEWARK, NJ07102 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) _____ Form filed by One Reporting Person __ X __ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Series K Mandatory Redeemable Preferred Shares 1,000,000 ( 1 ) I ( 2 ) By Prudential Retirement Insurance and Annuity Company, a wholly-owned subsidiary of the Reporting P Series L Mandatory Redeemable Preferred Shares 1,200,000 ( 3 ) I ( 2 ) By Prudential Retirement Insurance and Annuity Company, a wholly-owned subsidiary of the Reporting P 3.26% Series MM Senior Unsecured Notes due October 29, 2022 $ 1,000,000 ( 4 ) I By The Prudential Insurance Company of America, a wholly-owned subsidiary of the Reporting Person 3.26% Series MM Senior Unsecured Notes due October 29, 2022 $ 12,000,000 ( 4 ) I By The Gibraltar Life Insurance Co., Ltd., a wholly-owned subsidiary of the Reporting Person 3.26% Series MM Senior Unsecured Notes due October 29, 2022 $ 10,900,000 ( 4 ) I By Prudential Retirement Insurance and Annuity Company, a wholly-owned subsidiary of the Reporting P 3.26% Series MM Senior Unsecured Notes due October 29, 2022 $ 1,100,000 ( 4 ) I ( 5 ) By Prudential Arizona Reinsurance Universal Company, a wholly-owned subsidiary of the Reporting Pers

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other PRUDENTIAL FINANCIAL INC 751 BROAD ST NEWARK, NJ07102 X Prudential Retirement Insurance & Annuity Co prudentail retirement insurance and Annu 280 Trumbull Street Hartford, CT06103 X Signatures Prudential Financial, Inc. By: /s/Richard Baker, Second Vice President 02/13/2020 Signature of Reporting Person Date Prudential Retirement Insurance and Annuity Company By: PGIM, Inc., as investment manager By: /s/Callie Hamilton, Vice President 02/13/2020 Signature of Reporting Person Date

Explanation of Responses:

( 1 )Acquired on April 10, 2015. Issued by Kayne Anderson Energy Development Company (predecessor by merger to KYN). ( 2 )Preferred shares owned directly by Prudential Retirement Insurance and Annuity Company, a ten percent owner of a class, and indirectly owned by Prudential Financial, Inc., its parent holding company. ( 3 )Acquired on February 11, 2020. ( 4 )Acquired on October 29, 2014. ( 5 )As grantor of the PAR U Hartford Life Insurance Comfort Trust.

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