Sec Form 4 Filing - FRIEDBERG ALBERT @ VACCINEX, INC. - 2018-08-13

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person FRIEDBERG ALBERT 2. Issuer Name and Ticker or Trading Symbol VACCINEX, INC. [ VCNX] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) X __ Director X __ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) 181 BAY STREET, SUITE 250, 3. Date of Earliest Transaction (MM/DD/YY) 08/13/2018 (Street) TORONTO, A6M5J 2T3 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) _____ Form filed by One Reporting Person __ X __ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 08/13/2018 C 439,555 A 439,555 D Common Stock 08/13/2018 C 37,633 A 37,633 I By Pan-Atlantic Bank & Trust Ltd. ( 2 ) Common Stock 08/13/2018 C 500,570 A 944,864 I By FCMI Parent Co. ( 3 ) Common Stock 08/13/2018 C 599,957 A 1,544,821 I By FCMI Parent Co. ( 3 ) Common Stock 08/13/2018 C 204,145 A 1,748,966 I By FCMI Parent Co. ( 3 ) Common Stock 08/13/2018 C 480,822 A 2,229,788 I By FCMI Parent Co. ( 3 ) Common Stock 08/13/2018 C 683,681 A 2,913,469 I By FCMI Parent Co. ( 3 ) Common Stock 08/13/2018 P 1,875,000 A $ 12 4,788,469 I By FCMI Parent Co. ( 3 ) Common Stock 08/13/2018 P 583,333 A $ 12 583,333 I By Global Macro Hedge Fund Ltd. ( 6 )

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Series D Convertible Preferred Stock ( 1 ) 08/13/2018 C 4,395,604 ( 1 ) ( 1 ) Common Stock 439,555 ( 1 ) 0 D Series A Convertible Preferred Stock ( 1 ) 08/13/2018 C 376,334 ( 1 ) ( 1 ) Common Stock 37,633 ( 1 ) 0 I By Pan-Atlantic Bank & Trust Ltd. ( 2 ) Series A Convertible Preferred Stock ( 1 ) 08/13/2018 C 5,005,755 ( 1 ) ( 1 ) Common Stock 500,570 ( 1 ) 0 I By FCMI Parent Co. ( 3 ) Series B Convertible Preferred Stock ( 4 ) 08/13/2018 C 3,655,595 ( 4 ) ( 4 ) Common Stock 599,957 ( 1 ) 0 I By FCMI Parent Co. ( 3 ) Series B1 Convertible Preferred Stock ( 1 ) 08/13/2018 C 2,041,477 ( 1 ) ( 1 ) Common Stock 204,145 ( 1 ) 0 I By FCMI Parent Co. ( 3 ) Series B2 Convertible Preferred Stock ( 5 ) 08/13/2018 C 3,877,641 ( 5 ) ( 5 ) Common Stock 480,822 ( 5 ) 0 I By FCMI Parent Co. ( 3 ) Series D Convertible Preferred Stock ( 1 ) 08/13/2018 C 6,836,890 ( 1 ) ( 1 ) Common Stock 683,681 ( 1 ) 0 I By FCMI Parent Co. ( 3 ) Option (Right to Acquire) ( 7 ) ( 7 ) 08/13/2018 J( 7 ) 21,475,000 ( 7 ) ( 7 ) Common Stock 1,800,051 ( 7 ) 21,475,000 I By FCMI Parent Co. ( 3 )

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other FRIEDBERG ALBERT 181 BAY STREET, SUITE 250 TORONTO, A6M5J 2T3 X X FCMI Parent Co. 181 BAY STREET SUITE 250 TORONTO, A6M5J 2T3 X Signatures /s/ Scott E. Royer, Attorney-in-Fact 08/15/2018 Signature of Reporting Person Date FCMI PARENT CO. BY:/s/ Dan Scheiner, Vice President 08/15/2018 Signature of Reporting Person Date

Explanation of Responses:

( 1 )The reported securities converted into shares of Common Stock on a 1-for-10 basis immediately prior to the consummation of the Issuer's initial public offering. ( 2 )Albert D. Friedberg is the majority owner of Pan Atlantic Bank & Trust Ltd. and disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein. ( 3 )Mr. Friedberg is the majority owner, a director and the president of FCMI Parent Co. and disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein. ( 4 )The reported securities converted into shares of Common Stock on a 0.1641-for-1 basis immediately prior to the consummation of the Issuer's initial public offering. ( 5 )The reported securities converted into shares of Common Stock on a 0.124-for-1 basis immediately prior to the consummation of the Issuer's initial public offering. ( 6 )Mr. Friedberg possesses voting and dispositive power over the reported securities and disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein. ( 7 )Partnership interests in VX3 (DE) LP, or VX3, which are exchangeable into shares of Common Stock on a 1-for-0.05495 basis at the holder's option. On August 13, 2018, FCMI Parent Co. entered into an exchange agreement with the Issuer and the other partners of VX3 that provides each VX3 partner the right to exchange all, but not less than all, of its partnership interests in VX3 for shares of Common Stock. The option has no expiration date.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

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