Sec Form 4 Filing - Michels Douglas A @ ORASURE TECHNOLOGIES INC - 2012-07-09

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person Michels Douglas A 2. Issuer Name and Ticker or Trading Symbol ORASURE TECHNOLOGIES INC [ OSUR] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) X __ Director _____ 10% Owner X __ Officer (give title below) _____ Other (specify below) President & CEO (Last) (First) (Middle) 220 EAST FIRST STREET 3. Date of Earliest Transaction (MM/DD/YY) 07/09/2012 (Street) BETHLEHEM, PA18015 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common stock 07/09/2012 M 7,197 A $ 7.765 585,979 D Common stock 07/09/2012 M 54,903 A $ 5.598 640,882 D Common stock 07/09/2012 S( 1 ) 62,100 D $ 13.64 578,782 D Common stock 5,400 I By son.

11. Nature of Indirect Beneficial Ownership (Instr. 4) Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Non-qualified stock option $ 7.765 07/09/2012 M 7,197 ( 2 ) 06/22/2014 Common stock 7,197 $ 0 0 D Incentive stock option $ 5.598 07/09/2012 M 1,406 ( 3 ) 01/26/2015 Common stock 1,406 $ 0 0 D Non-qualified stock option $ 5.598 07/09/2012 M 53,497 ( 3 ) 01/26/2015 Common stock 53,497 $ 0 12,597 D

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other Michels Douglas A 220 EAST FIRST STREET BETHLEHEM, PA18015 X President & CEO Signatures Mark L. Kuna, As Attorney-In-Fact for Douglas A. Michels, (Power of Attorney previously filed) 07/11/2012 Signature of Reporting Person Date

Explanation of Responses:

( 1 )Sale pursuant to a predetermined sales plan, entered into on February 28, 2012, under Rule 10b5-1 of the Securities and Exchange Act of 1934. ( 2 )Nonqualified stock options granted on June 22, 2004, vesting over a four year period, with one-fourth of the options vesting on the first anniversary date of the grant and the remainder vesting ratably on a monthly basis, over the remaining 36 months. ( 3 )Stock options granted on January 26, 2005, vesting over a four year period, with one-fourth of the options vesting on the first anniversary date of the grant and the remainder vesting ratably on a monthly basis, over the remaining 36 months.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

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