Sec Form 4 Filing - Esfandiari Javan @ CHEMBIO DIAGNOSTICS, INC. - 2018-06-13

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person Esfandiari Javan 2. Issuer Name and Ticker or Trading Symbol CHEMBIO DIAGNOSTICS, INC. [ CEMI] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner X __ Officer (give title below) _____ Other (specify below) Chief Science/Tech Officer (Last) (First) (Middle) 3661 HORSEBLOCK ROAD 3. Date of Earliest Transaction (MM/DD/YY) 06/13/2018 (Street) MEDFORD, NY11763 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 06/13/2018 M 20,000 ( 1 ) A $ 5.64 111,258 D Common Stock 06/13/2018 F 11,345 ( 1 ) D 99,913 D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Options to purchase common stock $ 5.64 06/13/2018 M 20,000 03/11/2018 03/11/2021 Common Stock 20,000 $ 0 0 D

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other Esfandiari Javan 3661 HORSEBLOCK ROAD MEDFORD, NY11763 Chief Science/Tech Officer Signatures /s/ Javan Esfandiari 06/15/2018 Signature of Reporting Person Date

Explanation of Responses:

( 1 )The reporting person did not sell any shares of common stock. Rather, the reporting person exercised options to acquire 18,712 shares of common stock by submitting and relinquishing to the issuer (i) options to purchase an additional 1,288 shares of common stock and (ii) 10,057 shares of common stock. These additional options to purchase 1,288 shares of common stock and the 10,057 shares of common stock constituted the entire exercise price, using the 10-day volume weighted average trading price ended June 12, 2018 of $9.9432. As a result of these transactions, the reporting person increased his common stock ownership by a net addition of 8,655 shares.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

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