Sec Form 4 Filing - Reeve Emma @ PTC THERAPEUTICS, INC. - 2020-12-14

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person Reeve Emma 2. Issuer Name and Ticker or Trading Symbol PTC THERAPEUTICS, INC. [ PTCT] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) X __ Director _____ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) C/O PTC THERAPEUTICS, INC., 100 CORPORATE COURT 3. Date of Earliest Transaction (MM/DD/YY) 12/14/2020 (Street) SOUTH PLAINFIELD, NJ07080 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 12/14/2020 M( 1 ) 1,000 A $ 33.02 2,650 D Common Stock 12/14/2020 S( 1 ) 1,000 D $ 68 1,650 D Common Stock 12/14/2020 M( 1 ) 972 A $ 33.02 2,622 D Common Stock 12/14/2020 S( 1 ) 972 D $ 68 1,650 D Common Stock 12/15/2020 M( 1 ) 1,028 A $ 33.02 2,678 D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Stock Option (Right to Buy) $ 33.02 12/14/2020 M( 1 ) 1,000 ( 2 ) 01/21/2029 Common Stock 1,000 $ 33.02 13,000 D Stock Option (Right to Buy) $ 33.02 12/14/2020 M( 1 ) 972 ( 2 ) 01/21/2029 Common Stock 972 $ 33.02 12,028 D Stock Option (Right to Buy) $ 33.02 12/15/2020 M( 1 ) 1,028 ( 2 ) 01/21/2029 Common Stock 1,028 $ 33.02 11,000 D Stock Option (Right to Buy) $ 33.63 ( 3 ) 12/13/2028 Common Stock 14,000 14,000 D Stock Option (Right to Buy) $ 33.63 ( 2 ) 12/13/2028 Common Stock 1,167 1,167 D Stock Option (Right to Buy) $ 51.16 ( 4 ) 01/28/2030 Common Stock 10,000 10,000 D

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other Reeve Emma C/O PTC THERAPEUTICS, INC. 100 CORPORATE COURT SOUTH PLAINFIELD, NJ07080 X Signatures /s/ Avraham S. Adler, attorney-in-fact 12/16/2020 Signature of Reporting Person Date

Explanation of Responses:

( 1 )This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on August 29, 2020. ( 2 )Currently exercisable. ( 3 )This option award vests in thirty-six approximately equal monthly installments, commencing on January 14, 2019 and continuing on each successive monthly anniversary of thereafter, ending on the third year anniversary of the grant date. ( 4 )This option was granted on January 29, 2020 and vests over one year in twelve equal monthly installments, commencing on February 29, 2020.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

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