Sec Form 4 Filing - BAFFI ROBERT @ BIOMARIN PHARMACEUTICAL INC - 2010-03-10

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person BAFFI ROBERT 2. Issuer Name and Ticker or Trading Symbol BIOMARIN PHARMACEUTICAL INC [ BMRN] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner X __ Officer (give title below) _____ Other (specify below) EVP, Technical Operations (Last) (First) (Middle) C/O BIOMARIN PHARMACEUTICAL INC., 105 DIGITAL DRIVE 3. Date of Earliest Transaction (MM/DD/YY) 03/10/2010 (Street) NOVATO, CA94949 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 03/10/2010 03/10/2010 M 163,888 A $ 22 224,476 D Common Stock 03/10/2010 03/10/2010 S 163,888 D $ 22.5216 ( 1 ) 60,588 D Common Stock 05/04/2010 05/04/2010 G 876 ( 2 ) D $ 0 59,712 D Common Stock 05/05/2010 05/05/2010 G 1,353 ( 3 ) D $ 0 58,359 D Common Stock 11/02/2010 11/02/2010 G 473 ( 4 ) D $ 0 57,886 D Common Stock 05/04/2011 05/04/2011 G 1,447 ( 5 ) D $ 0 56,439 D Common Stock 11/14/2011 11/14/2011 G 333 ( 6 ) D $ 0 56,106 D Common Stock 05/01/2012 05/01/2012 G 920 ( 7 ) D $ 0 55,186 D Common Stock 11/02/2012 11/02/2012 G 161 ( 8 ) D $ 0 55,025 D Common Stock 01/22/2013 01/22/2013 G V 2,675 ( 9 ) D $ 0 52,350 D Common Stock 05/04/2010 05/04/2010 G 876 A $ 0 876 I Shares held by Baffi Family Trust Common Stock 05/05/2010 05/05/2010 G 1,353 A $ 0 2,229 I Shares held by Baffi Family Trust Common Stock 11/02/2010 11/02/2010 G 473 A $ 0 2,702 I Shares held by Baffi Family Trust Common Stock 05/04/2011 05/04/2011 G 1,447 A $ 0 4,149 I Shares held by Baffi Family Trust Common Stock 11/14/2011 11/14/2011 G 333 A $ 0 4,482 I Shares held by Baffi Family Trust Common Stock 05/01/2012 05/01/2012 G 920 A $ 0 5,402 I Shares held by Baffi Family Trust Common Stock 11/02/2012 11/02/2012 G 161 A $ 0 5,563 I Shares held by Baffi Family Trust Common Stock 01/22/2013 01/22/2013 G 2,675 A $ 0 8,238 I Shares held by Baffi Family Trust

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Stock Option (right to buy) Common Stock $ 22 03/10/2010 03/10/2010 M 8,335 06/09/2000( 10 ) 05/08/2010 Common Stock 8,335 $ 0 0 ( 12 ) D Stock Option (right to buy) Common Stock $ 22 03/10/2010 03/10/2010 M 155,553 11/09/2000( 11 ) 05/08/2010 Common Stock 155,553 $ 0 0 ( 12 ) D

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other BAFFI ROBERT C/O BIOMARIN PHARMACEUTICAL INC. 105 DIGITAL DRIVE NOVATO, CA94949 EVP, Technical Operations Signatures /s/ Laura Randall Woodhead, Attorney-in-Fact 03/14/2013 Signature of Reporting Person Date

Explanation of Responses:

( 1 )The price in Column 4 is a weighted average price. The prices actually received ranged from $22.50 and $22.5262. The reporting person will provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. ( 2 )On May 4, 2010 the reportng person gifted 876 shares of Common Stock to his family trust. The reporting person is the trustee. ( 3 )On May 5, 2010 the reportng person gifted 1353 shares of Common Stock to his family trust. The reporting person is the trustee. ( 4 )On November 2, 2010 the reportng person gifted 473 shares of Common Stock to his family trust. The reporting person is the trustee. ( 5 )On May 4, 2011 the reportng person gifted 1447 shares of Common Stock to his family trust. The reporting person is the trustee. ( 6 )On November 4, 2011 the reportng person gifted 333 shares of Common Stock to his family trust. The reporting person is the trustee. ( 7 )On May 1, 2012 the reportng person gifted 920 shares of Common Stock to his family trust. The reporting person is the trustee. ( 8 )On November 2, 2012 the reportng person gifted 161 shares of Common Stock to his family trust. The reporting person is the trustee. ( 9 )On January 22, 2010 the reportng person gifted 2675 shares of Common Stock to his family trust. The reporting person is the trustee. ( 10 )Original option grant vested 1/12th on 6/9/2000 and 1/12th on the 9th of every month thereafter. ( 11 )Original option grant vested 6/48ths on 11/9/2000 and 1/48th on the 9th of every month thereafter. ( 12 )Reflects the number of stock options that remain outstanding from this specific stock option grant following the reported transaction.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

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