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Sec Filings Insider Trading - Wedel Mark K - Portfolio Holdings (Majority Ownership)
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"Insiders might sell their shares for any number of reasons, but they buy them for only one: they think the price will rise"
- Peter Lynch ==>> What is insider trading>>
Insider Trading Transactions for Wedel Mark K
Wedel Mark K: Insider Trading and Stock Options
Common stock purchase or sale:
Transaction
& Date		 Reported
Date		 Company Symbol Insider
Relationship		 Shares
Traded		 Average
Price		 Total
Amount		 Shares
Ownership		 Filing
2007-07-06
Sale		 2007-07-10
6:21 pm		 ISIS PHARMACEUTICALS INC ISIS Wedel Mark K
(VP & Chief Medical Officer)		 5,200 $10.12 $52,626 6,603
(Direct)		 View
2007-07-02
Sale		 2007-07-03
5:08 pm		 ISIS PHARMACEUTICALS INC ISIS Wedel Mark K
(VP & Chief Medical Officer)		 902 $9.703 $8,752 6,603
(Direct)		 View
2007-05-09
Sale		 2007-05-11
5:06 pm		 ISIS PHARMACEUTICALS INC ISIS Wedel Mark K
(VP & Chief Medical Officer)		 2,800 $10.36 $29,019 6,603
(Direct)		 View
2007-05-02
Sale		 2007-05-04
6:55 pm		 ISIS PHARMACEUTICALS INC ISIS Wedel Mark K
(VP & Chief Medical Officer)		 2,000 $10.25 $20,500 6,603
(Direct)		 View
2007-04-25
Sale		 2007-04-27
7:43 pm		 ISIS PHARMACEUTICALS INC ISIS Wedel Mark K
(VP & Chief Medical Officer)		 13,711 $10.11 $138,618 6,603
(Direct)		 View
Other transactions:
Transaction
& Date		 Reported
Date		 Company Symbol Insider
Relationship		 Shares
Traded		 Average
Price		 Total
Amount		 Shares
Ownership		 Filing
2007-07-06
Exercise		 2007-07-10
6:21 pm		 ISIS PHARMACEUTICALS INC ISIS Wedel Mark K
(VP & Chief Medical Officer)		 5,200 $5.6 $29,118 11,803
(Direct)		 View
2007-07-01
Other		 2007-07-03
5:08 pm		 ISIS PHARMACEUTICALS INC ISIS Wedel Mark K
(VP & Chief Medical Officer)		 902 $8.228 $7,422 7,505
(Direct)		 View
2007-05-09
Exercise		 2007-05-11
5:06 pm		 ISIS PHARMACEUTICALS INC ISIS Wedel Mark K
(VP & Chief Medical Officer)		 2,800 $5.15 $14,420 9,403
(Direct)		 View
2007-05-02
Exercise		 2007-05-04
6:55 pm		 ISIS PHARMACEUTICALS INC ISIS Wedel Mark K
(VP & Chief Medical Officer)		 2,000 $5.15 $10,300 8,603
(Direct)		 View
2007-04-25
Exercise		 2007-04-27
7:43 pm		 ISIS PHARMACEUTICALS INC ISIS Wedel Mark K
(VP & Chief Medical Officer)		 10,000 $4.677 $46,769 20,317
(Direct)		 View
2007-01-01
Other		 2007-01-04
6:03 pm		 ISIS PHARMACEUTICALS INC ISIS Wedel Mark K
(VP & Chief Medical Officer)		 698 $5.143 $3,589 10,314
(Direct)		 View
2006-07-01
Other		 2006-07-05
6:40 pm		 ISIS PHARMACEUTICALS INC ISIS Wedel Mark K
(VP & Chief Medical Officer)		 1,162 $4.454 $5,176 9,616
(Direct)		 View
2006-01-01
Other		 2006-01-04
5:21 pm		 ISIS PHARMACEUTICALS INC ISIS Wedel Mark K
(VP & Chief Medical Officer)		 394 $3.357 $1,323 8,454
(Direct)		 View
2005-07-01
Other		 2005-07-06
5:57 pm		 ISIS PHARMACEUTICALS INC ISIS Wedel Mark K
(VP & Chief Medical Officer)		 856 $3.357 $2,874 8,060
(Direct)		 View
Stock options: Exercise, Award, Grant, Conversion
Transaction
& Date		 Reported
Date		 Exercisable
Expiration		 Company Symbol Insider
Relationship		 Shares
Traded		 Conversion
Price		 Shares
Ownership		 Filing
2007-07-06
Exercise		 2007-07-10
6:21 pm		 2007-01-03
2013-01-02		 ISIS PHARMACEUTICALS INC ISIS Wedel Mark K
(VP & Chief Medical Officer)		 1,895 $5.25 18,264
(Direct)		 View
2007-07-06
Exercise		 2007-07-10
6:21 pm		 2006-01-03
2012-01-02		 ISIS PHARMACEUTICALS INC ISIS Wedel Mark K
(VP & Chief Medical Officer)		 3,305 $5.8 17,543
(Direct)		 View
2007-05-09
Exercise		 2007-05-11
5:06 pm		 2006-01-01
2008-12-31		 ISIS PHARMACEUTICALS INC ISIS Wedel Mark K
(VP & Chief Medical Officer)		 2,800 $5.15 5,700
(Direct)		 View
2007-05-02
Exercise		 2007-05-04
6:55 pm		 2006-01-01
2008-12-31		 ISIS PHARMACEUTICALS INC ISIS Wedel Mark K
(VP & Chief Medical Officer)		 2,000 $5.15 8,500
(Direct)		 View
2007-04-25
Exercise		 2007-04-27
7:43 pm		 2007-01-03
2013-01-02		 ISIS PHARMACEUTICALS INC ISIS Wedel Mark K
(VP & Chief Medical Officer)		 5,625 $5.25 20,159
(Direct)		 View
2007-04-25
Exercise		 2007-04-27
7:43 pm		 2006-05-25
2012-05-24		 ISIS PHARMACEUTICALS INC ISIS Wedel Mark K
(VP & Chief Medical Officer)		 4,375 $3.94 5,625
(Direct)		 View
2007-01-02
Option Award		 2007-01-04
6:03 pm		 2008-01-02
2014-01-01		 ISIS PHARMACEUTICALS INC ISIS Wedel Mark K
(VP & Chief Medical Officer)		 37,535 $11.12 37,535
(Direct)		 View
2006-01-03
Option Award		 2006-01-04
5:21 pm		 2007-01-03
2013-01-02		 ISIS PHARMACEUTICALS INC ISIS Wedel Mark K
(VP & Chief Medical Officer)		 25,784 $5.25 25,784
(Direct)		 View
2005-05-25
Option Award		 2005-05-26
7:39 pm		 2009-05-25
2012-05-24		 ISIS PHARMACEUTICALS INC ISIS Wedel Mark K
(VP & Chief Medical Officer)		 10,000 $3.94 10,000
(Direct)		 View