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"Insiders might sell their shares for any number of reasons, but they buy them for only one:
they think the price will rise" - Peter Lynch ==>> What is insider trading>> |

| Transaction & Date | Reported Date |
Company | Symbol | Insider Relationship |
Shares Traded | Average Price | Total Amount |
Shares Ownership |
Filing |
| 2007-02-23 Sale |
2007-02-27 11:05 am | Vanda Pharmaceuticals Inc. | VNDA | KARABELAS ARGERIS N (Director) | 384,130 | $26.02 | $9,993,757 | 64,169 (Indirect) | View |
| 2007-02-22 Sale |
2007-02-23 11:57 am | Vanda Pharmaceuticals Inc. | VNDA | KARABELAS ARGERIS N (Director) | 72,600 | $26.82 | $1,947,328 | 88,830 (Indirect) |
View |
| 2007-02-20- -2007-02-21 Sale |
2007-02-22 4:09 pm |
Vanda Pharmaceuticals Inc. | VNDA | KARABELAS ARGERIS N (Director) | 437,000 | $27.03 | $11,811,740 | 93,491 (Indirect) |
View |
| 2006-12-12 Sale |
2006-12-14 4:12 pm | Vanda Pharmaceuticals Inc. | VNDA | KARABELAS ARGERIS N (Chairman of the Board Director) | 424,150 | $25.18 | $10,680,097 | 121,546 (Indirect) |
View |
| 2006-12-11 Sale | 2006-12-13 2:22 pm |
Vanda Pharmaceuticals Inc. | VNDA | KARABELAS ARGERIS N (Chairman of the Board Director) | 326,325 | $26.4 | $8,614,980 | 148,776 (Indirect) | View |
| 2006-11-27 Sale | 2006-11-29 3:04 pm | Vanda Pharmaceuticals Inc. | VNDA | KARABELAS ARGERIS N (Chairman of the Board Director) | 300,000 | $14.18 | $4,254,000 | 169,726 (Indirect) |
View |
| 2006-11-22 Sale |
2006-11-27 4:55 pm | Vanda Pharmaceuticals Inc. | VNDA | KARABELAS ARGERIS N (Chairman of the Board Director) | 300,000 | $14.12 | $4,236,000 | 188,986 (Indirect) | View |
| 2006-11-21 Sale | 2006-11-22 3:40 pm |
Vanda Pharmaceuticals Inc. | VNDA | KARABELAS ARGERIS N (Chairman of the Board Director) | 50,000 | $14.55 | $727,500 | 208,246 (Indirect) | View |
| 2006-11-17- -2006-11-20 Sale(A) | 2006-11-22 3:40 pm | Vanda Pharmaceuticals Inc. | VNDA | KARABELAS ARGERIS N (Chairman of the Board Director) | 320,000 | $14.41 | $4,612,000 | 211,456 (Indirect) | View |
| 2006-11-17- -2006-11-20 Sale | 2006-11-21 4:17 pm | Vanda Pharmaceuticals Inc. | VNDA | KARABELAS ARGERIS N (Chairman of the Board Director) | 320,000 | $14.41 | $4,612,000 | 310,495 (Indirect) |
View |
| 2006-11-10 Purchase | 2006-11-14 4:32 pm | HUMAN GENOME SCIENCES INC | HGSI | KARABELAS ARGERIS N (Director) | 12,500 | $12.15 | $151,875 | 12,500 (Direct) |
View |
| Transaction & Date |
Reported Date |
Company | Symbol | Insider Relationship |
Shares Traded |
Average Price |
Total Amount |
Shares Ownership | Filing |
| 2006-04-18 Purchase |
2006-04-18 3:36 pm | Vanda Pharmaceuticals Inc. | VNDA | KARABELAS ARGERIS N (Chairman of the Board Director) | 3,612,665 | $0 | $0 | 232,000 (Indirect) | View |
| 2004-10-18 Other | 2004-10-20 5:20 pm |
NITROMED INC | NTMD | KARABELAS ARGERIS N (Director) | 93,557 | $0 | $0 | 11,179 (Direct Indirect) |
View |
| 2004-09-27 Other |
2004-09-29 6:10 pm | NITROMED INC | NTMD | KARABELAS ARGERIS N (Director) | 718,677 | $0 | $0 | 1,415,234 (Indirect) |
View |
| 2003-11-10 Purchase |
2003-11-10 3:19 pm | NITROMED INC | NTMD | KARABELAS ARGERIS N (Director) | 2,051,533 | $0 | $0 | 2,051,533 (Indirect) | View |
| Transaction & Date |
Reported Date |
Exercisable Expiration | Company | Symbol | Insider Relationship |
Shares Traded | Conversion Price |
Shares Ownership |
Filing |
| 2008-05-14 Option Award |
2008-05-16 4:08 pm | N/A 2018-05-14 |
NITROMED INC | NTMD | KARABELAS ARGERIS N (Director) | 15,000 | $1.14 | 15,000 (Direct) | View |
| 2008-05-08 Option Award |
2008-05-12 10:51 am |
N/A 2018-05-07 | Vanda Pharmaceuticals Inc. | VNDA | KARABELAS ARGERIS N (Director) | 15,000 | $4.98 | 15,000 (Direct) |
View |
| 2008-05-08 Option Award | 2008-05-09 1:34 pm | N/A 2018-05-08 | HUMAN GENOME SCIENCES INC | HGSI | KARABELAS ARGERIS N (Director) | 16,000 | $5.97 | 16,000 (Direct) |
View |
| 2007-05-25 Option Award |
2007-05-30 2:09 pm | N/A 2017-05-25 | NITROMED INC | NTMD | KARABELAS ARGERIS N (Director) | 15,000 | $2.67 | 15,000 (Direct) |
View |
| 2007-05-16 Option Award |
2007-05-18 3:47 pm | N/A 2017-05-15 | Vanda Pharmaceuticals Inc. | VNDA | KARABELAS ARGERIS N (Director) | 14,037 | $19.59 | 14,037 (Indirect) |
View |
| 2007-05-16 Option Award | 2007-05-18 3:47 pm | N/A 2017-05-15 |
Vanda Pharmaceuticals Inc. | VNDA | KARABELAS ARGERIS N (Director) | 963 | $19.59 | 15,000 (Indirect) |
View |
| 2007-05-03 Option Award | 2007-05-07 1:24 pm |
N/A 2017-05-03 |
HUMAN GENOME SCIENCES INC | HGSI | KARABELAS ARGERIS N (Director) | 16,000 | $10.7 | 16,000 (Direct) |
View |
| 2007-03-12 Purchase |
2007-03-15 5:09 pm |
2007-03-12 2012-03-12 |
BIODELIVERY SCIENCES INTERNATIONAL INC | BDSI | KARABELAS ARGERIS N CDC IV LLC Ramsay David Russ LESCHLY JAN CDC Operations LLC (10% owner) | 1,000,000 | $3.8 | 1,000,000 (Direct) |
View |
| 2006-05-17 Option Award | 2006-05-19 6:17 pm | N/A 2011-05-17 | NITROMED INC | NTMD | KARABELAS ARGERIS N (Chairman, Interim CEO & Pres. Director) | 200,000 | $4.12 | 200,000 (Direct) | View |
| 2006-04-27 Option Award | 2006-04-28 2:45 pm |
N/A 2016-04-27 |
HUMAN GENOME SCIENCES INC | HGSI | KARABELAS ARGERIS N (Chairman Director) | 16,000 | $11.33 | 16,000 (Direct) |
View |
| 2006-04-18 Purchase | 2006-04-18 3:36 pm |
N/A N/A | Vanda Pharmaceuticals Inc. | VNDA | KARABELAS ARGERIS N (Chairman of the Board Director) | 4,774,500 | $0 | 0 (Indirect) |
View |
| 2006-04-18 Purchase |
2006-04-18 3:36 pm |
N/A N/A |
Vanda Pharmaceuticals Inc. | VNDA | KARABELAS ARGERIS N (Chairman of the Board Director) | 327,500 | $0 | 0 (Indirect) | View |
| 2006-04-18 Purchase | 2006-04-18 3:36 pm | N/A N/A | Vanda Pharmaceuticals Inc. | VNDA | KARABELAS ARGERIS N (Chairman of the Board Director) | 6,414,986 | $0 | 0 (Indirect) |
View |
| 2006-04-18 Purchase |
2006-04-18 3:36 pm | N/A N/A |
Vanda Pharmaceuticals Inc. | VNDA | KARABELAS ARGERIS N (Chairman of the Board Director) | 440,073 | $0 | 0 (Indirect) |
View |
| 2006-03-20 Option Award | 2006-03-22 5:05 pm | N/A 2016-03-20 |
NITROMED INC | NTMD | KARABELAS ARGERIS N (CEO and President Director) | 225,000 | $7.83 | 225,000 (Direct) |
View |
| 2005-09-01 Option Award |
2005-09-06 9:23 pm |
2005-10-01 2015-08-31 |
ANADYS PHARMACEUTICALS INC | ANDS | KARABELAS ARGERIS N (Director) | 5,000 | $12.16 | 5,000 (Direct) |
View |
| 2005-06-03 Option Award | 2005-06-07 6:28 pm |
2005-07-03 2015-06-02 | ANADYS PHARMACEUTICALS INC | ANDS | KARABELAS ARGERIS N (Director) | 5,000 | $8.37 | 5,000 (Direct) | View |
| 2005-05-26 Option Award | 2005-05-31 3:19 pm |
N/A 2015-05-26 | HUMAN GENOME SCIENCES INC | HGSI | KARABELAS ARGERIS N (Chairman Director) | 16,000 | $11.51 | 16,000 (Direct) | View |
| 2005-05-16 Option Award |
2005-05-18 2:09 pm | N/A 2015-05-16 |
NITROMED INC | NTMD | KARABELAS ARGERIS N (Director) | 15,000 | $14.99 | 15,000 (Direct) | View |
| 2004-06-14 Option Award | 2004-07-15 7:49 pm | N/A 2014-06-14 |
NITROMED INC | NTMD | KARABELAS ARGERIS N (Director 10% owner) | 10,000 | $6.95 | 10,000 (Direct) |
View |
| 2004-05-21 Option Award | 2004-05-25 1:08 pm |
N/A 2014-05-21 |
HUMAN GENOME SCIENCES INC | HGSI | KARABELAS ARGERIS N (Director) | 48,000 | $10.69 | 48,000 (Direct) | View |
| 2003-11-10 Purchase |
2003-11-10 3:19 pm | 2003-11-10 N/A |
NITROMED INC | NTMD | KARABELAS ARGERIS N (Director) | 1,667,644 | $0 | 0 (Indirect) |
View |
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