Insider Trading - Defiante Farmaceutica Lda - Portfolio Holdings (Majority Ownership)

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Sec Filings Insider Trading - Defiante Farmaceutica Lda - Portfolio Holdings (Majority Ownership)

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Insider Trading Transactions for Defiante Farmaceutica Lda

DEFIANTE FARMACEUTICA LDA: Insider Trading and Stock Options

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Common stock purchase or sale:

Transaction & Date	Reported Date	Company	Symbol	Insider Relationship	Shares Traded	Average Price	Total Amount	Shares Ownership	Filing
2008-01-30 Purchase	2008-02-01 2:36 pm	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	28,600	$2.049	$58,604	6,580,938 (Indirect)	View
2008-01-28 Purchase	2008-01-30 1:57 pm	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	400	$2.05	$820	6,552,338 (Indirect)	View
2008-01-24- -2008-01-25 Purchase	2008-01-28 12:11 pm	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	36,287	$2.045	$74,225	6,551,938 (Indirect)	View
2008-01-22- -2008-01-23 Purchase	2008-01-24 2:18 pm	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	29,133	$2.012	$58,630	6,515,651 (Indirect)	View
2008-01-14 Purchase^(A)	2008-01-24 2:14 pm	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	200	$2	$400	6,423,189 (Indirect)	View
2008-01-15- -2008-01-16 Purchase	2008-01-17 11:57 am	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	63,329	$2.014	$127,553	6,486,718 (Indirect)	View
2008-01-11- -2008-01-14 Purchase	2008-01-15 11:09 am	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	28,401	$1.999	$56,782	6,423,389 (Indirect)	View
2007-11-20 Purchase	2007-11-23 4:41 pm	QUESTCOR PHARMACEUTICALS INC	QSC	DEFIANTE FARMACEUTICA LDA CAVAZZA PAOLO APTAFIN S P A CAVAZZA CLAUDIO SIGMA TAU FINANZIARIA SPA SIGMA TAU INTERNATIONAL SA Chaumiere Consultadoria & Servicos SDC Unipessoal LDA Inverlochy Consultadoria & Servicos L.D.A. (10% owner)	2,446,782	$4.68	$11,450,940	7,248,227 (Indirect)	View
2007-11-20 Sale	2007-11-23 4:41 pm	QUESTCOR PHARMACEUTICALS INC	QSC	DEFIANTE FARMACEUTICA LDA CAVAZZA PAOLO APTAFIN S P A CAVAZZA CLAUDIO SIGMA TAU FINANZIARIA SPA SIGMA TAU INTERNATIONAL SA Chaumiere Consultadoria & Servicos SDC Unipessoal LDA Inverlochy Consultadoria & Servicos L.D.A. (10% owner)	2,446,782	$4.68	$11,450,940	0 (Direct)	View
2007-11-13 Purchase	2007-11-15 1:12 pm	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	54,640	$2.042	$111,575	6,394,988 (Indirect)	View
2007-11-07- -2007-11-08 Purchase	2007-11-09 3:51 pm	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	17,357	$2.048	$35,548	6,340,348 (Indirect)	View
2007-11-05 Purchase	2007-11-07 11:33 am	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	40,255	$2.046	$82,362	6,322,991 (Indirect)	View
2007-11-01- -2007-11-02 Purchase	2007-11-05 12:05 pm	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	54,119	$2.049	$110,886	6,282,736 (Indirect)	View
2007-10-19 Purchase	2007-10-23 12:29 pm	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	25,000	$2.05	$51,250	6,228,617 (Indirect)	View
2007-10-17- -2007-10-18 Purchase	2007-10-19 2:19 pm	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	41,269	$2.05	$84,599	6,203,617 (Indirect)	View
2007-10-15- -2007-10-16 Purchase	2007-10-17 5:05 pm	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	70,000	$2.056	$143,950	6,162,348 (Indirect)	View
2007-10-01- -2007-10-02 Purchase	2007-10-03 12:58 pm	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	24,337	$1.947	$47,389	6,092,348 (Indirect)	View
2006-12-20 Purchase	2006-12-22 4:06 pm	QUESTCOR PHARMACEUTICALS INC	QSC	DEFIANTE FARMACEUTICA LDA SIGMA TAU INTERNATIONAL SA APTAFIN S P A CAVAZZA CLAUDIO CAVAZZA PAOLO SIGMA TAU FINANZIARIA SPA Chaumiere Consultadoria & Servicos SDC Unipessoal LDA Inverlochy Consultadoria & Servicos L.D.A. (10% owner)	9,402,890	$1.5	$14,104,335	4,701,445 (Indirect)	View
2006-12-20 Sale	2006-12-22 4:06 pm	QUESTCOR PHARMACEUTICALS INC	QSC	DEFIANTE FARMACEUTICA LDA SIGMA TAU INTERNATIONAL SA APTAFIN S P A CAVAZZA CLAUDIO CAVAZZA PAOLO SIGMA TAU FINANZIARIA SPA Chaumiere Consultadoria & Servicos SDC Unipessoal LDA Inverlochy Consultadoria & Servicos L.D.A. (10% owner)	9,402,890	$1.5	$14,104,335	0 (Direct Indirect)	View
2006-12-21 Purchase	2006-12-22 09:46 am	REGENERX BIOPHARMACEUTICALS INC	RGN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	833,333	$1.8	$1,499,999	12,011,185 (Indirect)	View
2006-12-13 Purchase	2006-12-15 5:09 pm	QUESTCOR PHARMACEUTICALS INC	QSC	DEFIANTE FARMACEUTICA LDA SIGMA TAU INTERNATIONAL SA APTAFIN S P A CAVAZZA CLAUDIO CAVAZZA PAOLO SIGMA TAU FINANZIARIA SPA (10% owner)	690,000	$1.45	$1,000,500	2,446,782 (Indirect)	View
2006-03-06 Purchase	2006-03-08 7:12 pm	REGENERX BIOPHARMACEUTICALS INC	RGN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	731,850	$2.81	$2,056,498	10,914,694 (Indirect)	View
2005-06-22 Purchase	2005-06-24 5:08 pm	REGENERX BIOPHARMACEUTICALS INC	RGN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	307,692	$3.25	$999,999	984,615 (Direct Indirect)	View
2005-06-17 Purchase	2005-06-21 5:03 pm	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	134,237	$4.803	$644,682	4,799,911 (Indirect)	View
2005-06-15- -2005-06-16 Purchase^(A)	2005-06-17 5:34 pm	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	73,516	$4.523	$332,515	4,665,674 (Indirect)	View
2005-06-15- -2005-06-16 Purchase	2005-06-17 12:49 pm	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	73,516	$4.523	$332,515	4,665,674 (Indirect)	View
2005-06-10- -2005-06-13 Purchase	2005-06-14 4:27 pm	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	150,000	$4.18	$626,950	4,590,558 (Indirect)	View
2005-06-01 Purchase	2005-06-03 12:52 pm	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	6,900	$2.578	$17,788	3,828,558 (Indirect)	View
2005-05-26 Purchase	2005-05-31 4:10 pm	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	100,000	$2.432	$243,180	3,821,658 (Indirect)	View
2005-05-24- -2005-05-25 Purchase	2005-05-26 3:52 pm	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	150,000	$2.381	$357,170	3,721,658 (Indirect)	View
2005-04-18 Purchase	2005-04-19 3:03 pm	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	481	$2.7	$1,299	3,537,858 (Indirect)	View
2005-04-14- -2005-04-15 Purchase	2005-04-18 3:47 pm	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	29,505	$2.785	$82,177	3,537,377 (Indirect)	View
2005-04-13 Purchase	2005-04-15 7:48 pm	QUESTCOR PHARMACEUTICALS INC	QSC	DEFIANTE FARMACEUTICA LDA SIGMA TAU INTERNATIONAL SA SIGMA TAU FINANZIARIA SPA APTAFIN S P A CAVAZZA CLAUDIO CAVAZZA PAOLO (10% owner)	100,000	$0.65	$65,000	100,000 (Indirect)	View
2005-04-06 Purchase	2005-04-07 6:43 pm	QUESTCOR PHARMACEUTICALS INC	QSC	DEFIANTE FARMACEUTICA LDA SIGMA TAU INTERNATIONAL SA SIGMA TAU FINANZIARIA SPA APTAFIN S P A CAVAZZA CLAUDIO CAVAZZA PAOLO (10% owner)	100,000	$0.7138	$71,380	549,100 (Indirect)	View

(A) Indicate amendment filing.

Other transactions:

Transaction & Date	Reported Date	Company	Symbol	Insider Relationship	Shares Traded	Average Price	Total Amount	Shares Ownership	Filing
2006-07-14 Exercise	2006-07-18 2:02 pm	REGENERX BIOPHARMACEUTICALS INC	RGN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	263,158	$1.5	$394,737	11,177,852 (Indirect)	View
2005-12-16 Exercise	2005-12-20 1:52 pm	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	5,000	$5	$25,000	6,068,011 (Indirect)	View
2005-06-17 Exercise	2005-06-21 5:03 pm	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	1,236,100	$5	$6,180,500	6,063,011 (Indirect)	View
2005-06-13 Exercise	2005-06-14 4:27 pm	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	1,600	$5	$8,000	4,592,158 (Indirect)	View
2005-06-06- -2005-06-07 Exercise	2005-06-08 2:29 pm	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	612,000	$2.5	$1,530,000	4,440,558 (Indirect)	View
2005-05-06 Exercise	2005-05-10 3:10 pm	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	33,800	$5	$169,000	3,571,658 (Indirect)	View
2005-04-15 Other	2005-04-19 5:58 pm	QUESTCOR PHARMACEUTICALS INC	QSC	DEFIANTE FARMACEUTICA LDA SIGMA TAU INTERNATIONAL SA SIGMA TAU FINANZIARIA SPA APTAFIN S P A CAVAZZA CLAUDIO CAVAZZA PAOLO (10% owner)	1,265,822	$0	$0	0 (Indirect)	View
2005-03-30 Exercise	2005-04-01 2:11 pm	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	500	$5	$2,500	3,507,872 (Indirect)	View
2004-09-03 Exercise	2004-09-07 4:40 pm	REGENERX BIOPHARMACEUTICALS INC	RGRX.OB	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	1,382,488	$1.085	$1,499,999	9,875,151 (Indirect)	View

Stock options: Exercise, Award, Grant, Conversion

Transaction & Date	Reported Date	Exercisable Expiration	Company	Symbol	Insider Relationship	Shares Traded	Conversion Price	Shares Ownership	Filing
2006-12-21 Other	2006-12-22 09:46 am	2006-12-21 2011-12-21	REGENERX BIOPHARMACEUTICALS INC	RGN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	1	$2.75	1 (Indirect)	View
2006-07-14 Exercise	2006-07-18 2:02 pm	2004-01-23 2006-07-23	REGENERX BIOPHARMACEUTICALS INC	RGN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	1	$1.5	0 (Indirect)	View
2006-03-06 Other	2006-03-08 7:12 pm	2006-09-16 2011-03-15	REGENERX BIOPHARMACEUTICALS INC	RGN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	1	$4.06	1 (Indirect)	View
2005-12-16 Exercise	2005-12-20 1:52 pm	2005-06-08 2005-12-16	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	50	$5	0 (Indirect)	View
2005-06-17 Exercise	2005-06-21 5:03 pm	2005-06-17 2005-06-17	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	12,631	$5	60 (Indirect)	View
2005-06-13 Exercise	2005-06-14 4:27 pm	N/A 2005-06-17	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	16	$5	12,691 (Indirect)	View
2005-06-06 Exercise	2005-06-08 2:29 pm	N/A 2005-06-17	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	3,000	$2.5	3,120 (Indirect)	View
2005-06-07 Exercise	2005-06-08 2:29 pm	N/A 2005-06-17	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	3,120	$2.5	0 (Indirect)	View
2005-05-06 Exercise	2005-05-10 3:10 pm	N/A 2005-06-17	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	338	$5	12,707 (Indirect)	View
2005-04-15 Other	2005-04-19 5:58 pm	N/A 2005-04-15	QUESTCOR PHARMACEUTICALS INC	QSC	DEFIANTE FARMACEUTICA LDA SIGMA TAU INTERNATIONAL SA SIGMA TAU FINANZIARIA SPA APTAFIN S P A CAVAZZA CLAUDIO CAVAZZA PAOLO (10% owner)	0	$1.58	0 (Indirect)	View
2005-03-30 Exercise	2005-04-01 2:11 pm	N/A 2005-06-17	SCICLONE PHARMACEUTICALS INC	SCLN	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	5	$5	13,045 (Indirect)	View
2005-03-08 Other	2005-03-10 3:49 pm	N/A 2005-03-15	QUESTCOR PHARMACEUTICALS INC	QSC	DEFIANTE FARMACEUTICA LDA SIGMA TAU INTERNATIONAL SA SIGMA TAU FINANZIARIA SPA APTAFIN S P A CAVAZZA CLAUDIO CAVAZZA PAOLO (10% owner)	0	$1.58	0 (Indirect)	View
2005-03-08 Other	2005-03-10 3:49 pm	N/A 2005-04-15	QUESTCOR PHARMACEUTICALS INC	QSC	DEFIANTE FARMACEUTICA LDA SIGMA TAU INTERNATIONAL SA SIGMA TAU FINANZIARIA SPA APTAFIN S P A CAVAZZA CLAUDIO CAVAZZA PAOLO (10% owner)	0	$1.58	0 (Indirect)	View
2004-09-02 Other	2004-09-07 4:40 pm	N/A N/A	REGENERX BIOPHARMACEUTICALS INC	RGRX.OB	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	2	$1.085	2 (Indirect)	View
2004-09-03 Exercise	2004-09-07 4:40 pm	N/A N/A	REGENERX BIOPHARMACEUTICALS INC	RGRX.OB	DEFIANTE FARMACEUTICA LDA SIGMA TAU FINANZIARIA SPA (10% owner)	2	$1.085	0 (Indirect)	View

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