Sec Form 4 Filing - COTTIER GILLES @ SIGMA ALDRICH CORP - 2014-02-10

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person COTTIER GILLES 2. Issuer Name and Ticker or Trading Symbol SIGMA ALDRICH CORP [ SIAL] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner X __ Officer (give title below) _____ Other (specify below) EVP & Pres. SAFC Commercial (Last) (First) (Middle) C/O SIGMA-ALDRICH CORPORATION, 3050 SPRUCE ST 3. Date of Earliest Transaction (MM/DD/YY) 02/10/2014 (Street) ST LOUIS, MO63103 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 02/10/2014 A 4,096 ( 1 ) A $ 0 30,205 D Common Stock 02/10/2014 F 1,398 D $ 93.07 28,807 D Common Stock 02/11/2014 S 11,000 D $ 94 17,807 D Common Stock 02/11/2014 M 17,600 A $ 41.62 35,407 D Common Stock 02/11/2014 S 17,600 D $ 94 17,807 D Common Stock 02/11/2014 M 2,664 A $ 37.56 20,471 D Common Stock 02/11/2014 M 2,057 A $ 48.61 22,528 D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares NQ Stock Option Right to Buy $ 41.62 02/11/2014 M 17,600 02/16/2008( 2 ) 02/16/2017 Common Stock 17,600 $ 0 0 D ISO Stock Option Right To Buy $ 37.56 02/11/2014 M 2,664 02/17/2010( 3 ) 02/17/2019 Common Stock 2,664 $ 0 0 D ISO Stock Option Right To Buy $ 48.61 02/11/2014 M 2,057 02/16/2011( 4 ) 02/16/2020 Common Stock 2,057 $ 0 0 D NQ Stock Option Right to Buy $ 93.07 02/10/2014 A 14,701 02/10/2015( 5 ) 02/10/2024 Common Stock 14,701 $ 0 14,701 D ISO Stock Option Right To Buy $ 93.07 02/10/2014 A 1,074 02/10/2015( 5 ) 02/10/2024 Common Stock 1,074 $ 0 1,074 D Restricted Stock Unit $ 0 ( 6 ) 02/10/2014 A 2,430 02/10/2017 02/10/2017 Common Stock 2,430 $ 0 2,430 D

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other COTTIER GILLES C/O SIGMA-ALDRICH CORPORATION 3050 SPRUCE ST ST LOUIS, MO63103 EVP & Pres. SAFC Commercial Signatures /s/ Jesica Betts, by Power of Attorney 02/12/2014 Signature of Reporting Person Date

Explanation of Responses:

( 1 )The shares represent the payout of the 2011-2013 Performance Share award. ( 2 )The options vested in three equal installments on February 16, 2008, 2009, and 2010. ( 3 )The options vested in three equal installments on February 17, 2010, 2011, and 2012. ( 4 )The options vested in three equal installments on February 16, 2011, 2012, and 2013. ( 5 )The options vest in three equal annual installments: one-third on 2/10/2015; one-third on 2/10/2016; and one-third on 2/10/2017. ( 6 )Each restricted stock unit represents a contingent right to receive one share of SIAL common stock.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
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