Sec Form 4 Filing - Bostjancic John J. @ SeaSpine Holdings Corp - 2023-01-05

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person Bostjancic John J. 2. Issuer Name and Ticker or Trading Symbol SeaSpine Holdings Corp [ SPNE] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner X __ Officer (give title below) _____ Other (specify below) Chief Financial Officer (Last) (First) (Middle) C/O SEASPINE HOLDINGS CORPORATION, 5770 ARMADA DRIVE 3. Date of Earliest Transaction (MM/DD/YY) 01/05/2023 (Street) CARLSBAD, CA92008 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 01/05/2023 D 102,563 D 0 D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Restricted Stock Units ( 2 ) 01/05/2023 D 13,840 ( 3 ) ( 3 ) Common Stock 13,840 ( 4 ) 0 D Restricted Stock Units ( 2 ) 01/05/2023 D 51,795 ( 5 ) ( 5 ) Common Stock 51,795 ( 6 ) 0 D Employee Stock Option (Right to Buy) $ 15.68 01/05/2023 D 62,000 ( 7 ) 08/01/2023 Common Stock 62,000 ( 8 ) 0 D Employee Stock Option (Right to Buy) $ 14.19 01/05/2023 D 64,599 ( 9 ) 01/27/2024 Common Stock 64,599 ( 10 ) 0 D Employee Stock Option (Right to Buy) $ 18.24 01/05/2023 D 17,818 ( 11 ) 01/01/2027 Common Stock 17,818 ( 12 ) 0 D Employee Stock Option (Right to Buy) $ 12.01 01/05/2023 D 55,746 ( 13 ) 01/01/2028 Common Stock 55,746 ( 14 ) 0 D Employee Stock Option (Right to Buy) $ 9.93 01/05/2023 D 6,089 ( 15 ) 04/23/2028 Common Stock 6,089 ( 16 ) 0 D Employee Stock Option (Right to Buy) $ 16.86 01/05/2023 D 69,128 ( 17 ) 01/28/2029 Common Stock 69,128 ( 18 ) 0 D Employee Stock Option (Right to Buy) $ 12.67 01/05/2023 D 43,163 ( 19 ) 02/28/2030 Common Stock 43,163 ( 20 ) 0 D Employee Stock Option (Right to Buy) $ 15 01/05/2023 D 21,704 ( 19 ) 02/28/2030 Common Stock 21,704 ( 21 ) 0 D

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other Bostjancic John J. C/O SEASPINE HOLDINGS CORPORATION 5770 ARMADA DRIVE CARLSBAD, CA92008 Chief Financial Officer Signatures /s/Paul Benny, Attorney-in-Fact for Renee Gaeta 01/09/2023 Signature of Reporting Person Date

Explanation of Responses:

( 1 )Disposed of pursuant to the Agreement and Plan of Merger by and among the issuer, SeaSpine Holdings Corporation, which became effective on January 5, 2023, in exchange for 42,696 Orthofix Medical Inc. ("Orthofix") ordinary shares having a market value of $22.76 per share at the effective time of the merger. ( 2 )Each restricted stock unit represents a contingent right to receive one share of SeaSpine Holdings Corporation common stock. ( 3 )The restricted stock units vest in three equal installments on each of January 28, 2022, 2023 and 2024. ( 4 )These restricted stock units were assumed by Orthofix in the merger and replaced by 5,761 Orthofix restricted stock units. ( 5 )The restricted stock units vest in three equal installments on each of February 28, 2023, 2024 and 2025. ( 6 )These restricted stock units were assumed by Orthofix in the merger and replaced by 21,562 Orthofix restricted stock units. ( 7 )The option vests as to 25% of the underlying shares on May 1, 2016 and the remaining 75% in twelve substantially equal quarterly installments thereafter. ( 8 )This option was assumed by Orthofix in the merger and replaced with an option to purchase 25,810 shares of Orthofix at a price of $37.67 per share. ( 9 )The option vests in sixteen substantially equal quarterly installments beginning on March 31, 2016. ( 10 )This option was assumed by Orthofix in the merger and replaced with an option to purchase 26,892 shares of Orthofix at a price of $34.09 per share. ( 11 )The option vests as to 25% of the underlying shares on January 1, 2020 and the remaining 75% in twelve substantially equal quarterly installments thereafter. ( 12 )This option was assumed by Orthofix in the merger and replaced with an option to purchase 7,417 shares of Orthofix at a price of $43.82 per share. ( 13 )The option vests as to 25% of the underlying shares on January 1, 2021 and the remaining 75% in twelve substantially equal quarterly installments thereafter. ( 14 )This option was assumed by Orthofix in the merger and replaced with an option to purchase 23,207 shares of Orthofix at a price of $28.85 per share. ( 15 )The option fully vested and became exercisable on June 21, 2020. ( 16 )This option was assumed by Orthofix in the merger and replaced with an option to purchase 2,534 shares of Orthofix at a price of $23.86 per share. ( 17 )The option vests as to 25% of the underlying shares on January 28, 2022 and the remaining 75% in twelve substantially equal quarterly installments thereafter. ( 18 )This option was assumed by Orthofix in the merger and replaced with an option to purchase 28,777 shares of Orthofix at a price of $40.50 per share. ( 19 )The option vests as to 25% of the underlying shares on February 28, 2023 and the remaining 75% in twelve substantially equal quarterly installments thereafter. ( 20 )This option was assumed by Orthofix in the merger and replaced with an option to purchase 17,968 shares of Orthofix at a price of $30.44 per share. ( 21 )This option was assumed by Orthofix in the merger and replaced with an option to purchase 9,035 shares of Orthofix at a price of $36.04 per share.

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