Sec Form 4 Filing - DOERR L JOHN @ AMYRIS, INC. - 2023-06-05

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person DOERR L JOHN 2. Issuer Name and Ticker or Trading Symbol AMYRIS, INC. [ AMRS] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) X __ Director X __ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) C/O 1180 SAN CARLOS AVENUE, #717 3. Date of Earliest Transaction (MM/DD/YY) 06/05/2023 (Street) SAN CARLOS, CA94070 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) _____ Form filed by One Reporting Person __ X __ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares 2019 LSA $ 3 06/05/2023 D 06/05/2023 07/01/2023 Common Stock 21,004,799 ( 3 ) ( 4 ) 0 I By Foris Ventures, LLC ( 1 ) ( 2 ) 2019 LSA $ 3 06/05/2023 A 06/05/2023 07/01/2024 Common Stock 21,004,799 ( 3 ) ( 4 ) $ 63,014,396.78 I By Foris Ventures, LLC ( 1 ) ( 2 )

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other DOERR L JOHN C/O 1180 SAN CARLOS AVENUE, #717 SAN CARLOS, CA94070 X X Foris Ventures, LLC 1180 SAN CARLOS AVENUE, #717 SAN CARLOS, CA94070 X Doerr Ann Howland 1180 SAN CARLOS AVENUE, #717 SAN CARLOS, CA94070 X Hager Barbara 1180 SAN CARLOS AVENUE, #717 SAN CARLOS, CA94070 X Vallejo Ventures Trust UTA 21296 1180 SAN CARLOS AVENUE, #717 SAN CARLOS, CA94070 X Signatures /s/ L. John Doerr, by Barbara Hager as his attorney in fact 06/07/2023 Signature of Reporting Person Date /s/ Ann Howland Doerr, by Barbara Hager as her attorney in fact 06/07/2023 Signature of Reporting Person Date /s/ Vallejo Ventures Trust UTA 21296, by Barbara Hager as Special Trustee 06/07/2023 Signature of Reporting Person Date /s/ Foris Ventures, LLC, by Barbara Hager as manager 06/07/2023 Signature of Reporting Person Date /s/ Barbara Hager 06/07/2023 Signature of Reporting Person Date

Explanation of Responses:

( 1 )L. John Doerr ("John Doerr ") indirectly holds all of the membership interests in Foris Ventures, LLC ("FV"). John Doerr disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein. ( 2 )Barbara Hager, the manager of FV, may be deemed to have sole power to vote and dispose of the shares held by FV. The Vallejo Ventures Trust U/T/A 2/12/96 ("VVT"), the member of FV, may be deemed to have sole power to vote and dispose of these securities and John Doerr and Ann Doerr, the trustees of VVT, and Barbara Hager, the special trustee of VVT, may be deemed to have shared power to vote and dispose of the reported securities. Each of John Doerr , Ann Doerr and Barbara Hager disclaims beneficial ownership of the reported securities except to the extent of their pecuniary interest therein. FV and VVT are represented on the Issuer's board of directors by John Doerr. Accordingly, each of Ann Doerr, Barbara Hager, FV and VVT are deemed to be a director by deputization. ( 3 )On June 5, 2023, FV entered into that certain Omnibus Amendment Agreement, dated as of June 5, 2023 (the "Omnibus Amendment Agreement"), with the Issuer and the other parties thereto, to that certain Amended and Restated Loan and Security Agreement, dated as of October 28, 2019, by and between the Issuer, FV and the other parties thereto (as amended and restated from time to time, the "2019 LSA"). The Omnibus Amendment Agreement amended the 2019 LSA to extend the maturity date from July 1, 2023 to July 1, 2024, among other things. As of June 5, 2023, 16,680,334 shares of the issuer's common stock (the "Common Stock") are issuable upon conversion of the 2019 LSA in respect of an outstanding principal amount of $50.0 million and 4,324,465 shares of Common Stock are issuable upon conversion of accrued and unpaid interest of $13.0 million, reflecting a fixed conversion price of $3.00 per share of Common Stock. ( 4 )(Continued from Footnote 3) The 2019 LSA accrues interest at 6% per annum, subject to certain default interest provisions in the event of a default under the 2019 LSA.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

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