Sec Form 4 Filing - Williams Michelle LeRoux @ OSIRIS THERAPEUTICS, INC. - 2014-03-13

Insider filing report for Changes in Beneficial Ownership
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FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP
Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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1. Name and Address of Reporting Person
Williams Michelle LeRoux
2. Issuer Name and Ticker or Trading Symbol
OSIRIS THERAPEUTICS, INC. [ OSIR]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
X __ Officer (give title below) _____ Other (specify below)
Chief Scientific Officer
(Last) (First) (Middle)
7015 ALBERT EINSTEIN DRIVE
3. Date of Earliest Transaction (MM/DD/YY)
03/13/2014
(Street)
COLUMBIA, MD21046
4. If Amendment, Date Original Filed (MM/DD/YY)
6. Individual or Joint/Group Filing (Check Applicable Line)
__ X __ Form filed by One Reporting Person
_____ Form filed by More than One Reporting Person
(City) (State) (Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 03/13/2014 M 25,000 A $ 7.74 25,000 D
Common Stock 03/13/2014 M 18,750 A $ 7.13 43,750 D
Common Stock 03/13/2014 M 6,250 A $ 5.08 50,000 D
Common Stock 03/13/2014 S 50,000 D $ 14.1385 0 D
Common Stock 03/14/2014 M 11,934 A $ 12.01 11,934 D
Common Stock 03/14/2014 S 11,934 D $ 13.9106 0 D
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(MM/DD/YY)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Non-Qualified Stock Option (right to buy) $ 7.74 03/13/2014 M 18,747 03/12/2012 03/12/2020 Common Stock 18,747 $ 7.74 150,003 D
Incentive Stock Option (right to buy) $ 7.74 03/13/2014 M 6,253 03/12/2011 03/12/2020 Common Stock 6,253 $ 7.74 143,750 D
Non-Qualified Stock Option (right to buy) $ 7.13 03/13/2014 M 14,908 02/14/2012 02/14/2021 Common Stock 14,908 $ 7.13 128,842 D
Incentive Stock Option (right to buy) $ 7.13 03/13/2014 M 3,842 02/14/2012 02/14/2021 Common Stock 3,842 $ 7.13 125,000 D
Non-Qualified Stock Option (right to buy) $ 5.08 03/13/2014 M 6,249 03/23/2013 03/23/2022 Common Stock 6,249 $ 5.08 118,751 D
Incentive Stock Option (right to buy) $ 5.08 03/13/2014 M 1 03/23/2013 03/23/2022 Common Stock 1 $ 5.08 118,750 D
Non-Qualified Stock Option (right to buy) $ 12.01 03/14/2014 M 7,746 02/04/2009 02/04/2018 Common Stock 7,746 $ 12.01 111,004 D
Incentive Stock Option (right to buy) $ 12.01 03/14/2014 M 4,188 02/04/2009 02/04/2018 Common Stock 4,188 $ 12.01 106,896 D
Reporting Owners
Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
Williams Michelle LeRoux
7015 ALBERT EINSTEIN DRIVE
COLUMBIA, MD21046
Chief Scientific Officer
Signatures
Michelle L. Williams 03/17/2014
Signature of Reporting Person Date
Explanation of Responses:

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

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